A Phase Response Curve to Single Bright Light Pulses in Human Subjects
نویسندگان
چکیده
منابع مشابه
A phase response curve to single bright light pulses in human subjects.
The circadian pacemaker is differentially sensitive to the resetting effects of retinal light exposure, depending upon the circadian phase at which the light exposure occurs. Previously reported human phase response curves (PRCs) to single bright light exposures have employed small sample sizes, and were often based on relatively imprecise estimates of circadian phase and phase resetting. In th...
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Using 'classical' experimental protocols, a human phase-response curve (PRC) to a single 3-h bright light pulse has been established. When the light pulse was centred slightly before the time of body temperature minimum, the circadian system delayed, whilst a pulse slightly after the minimum advanced it. Maximum phase shifts were about 2 h. When light pulses over 3 successive cycles were used, ...
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It has been shown in animal studies that exposure to brief pulses of bright light can phase shift the circadian pacemaker and that the resetting action of light is most efficient during the first minutes of light exposure. In humans, multiple consecutive days of exposure to brief bright light pulses have been shown to phase shift the circadian pacemaker. The aim of the present study was to dete...
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Light is the dominant environmental time cue for circadian clocks. In 1998, bright, narrow-spectrum blue light exposure to the back of the knees was reported to reset the human circadian pacemaker (HCP) (1). Science recognized the widely cited report as among the top discoveries that year to “transform our ideas about the natural world” and reported that several groups had repeated the finding ...
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The current status of the software package PHASE for the propagation of coherent light pulses along a synchrotron radiation beamline is presented. PHASE is based on an asymptotic expansion of the Fresnel-Kirchhoff integral (stationary phase approximation) which is usually truncated at the 2 order. The limits of this approximation as well as possible extensions to higher orders are discussed. Th...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2003
ISSN: 0022-3751,1469-7793
DOI: 10.1113/jphysiol.2003.040477